Medication is a common first-line treatment for moms with moderate to severe PPD, but some women are afraid of side effects and risks. For some, the risk of not taking medication can be worse than the risk of taking them. Medication addresses the brain chemistry that has been altered by PPD/PPA. Most side effects, if any, get better as your body adjusts to the medication. You can work closely with your doctor to address any bothersome sensations or reactions while on medication. The point is to make you feel better, not worse. Of course, if you’re adverse to drugs of any kind, there are alternate therapies and treatments for you and your doctor to explore.